Cell Host & Microbe published a comment article written by Iván C. Acosta and Francis Alonzo III titled “Antibiotic treatment ignites a fire that lasts” and highlighted Qing Tang’s recent research.

Abstract: Tissue damage and persistent inflammation are distinctive features of antibiotic-resistant chronic infections. In this issue of Cell Host & Microbe, Tang et al. demonstrate that anti-folate antibiotics trigger the synthesis of a bacterial second messenger, which induces an exuberant immune response and establishes a paradigm for chronic infection.